Return to site
Return to site

Why Is Tablet Hardness Testing Essential in Pharmaceutical Manufacturing?

· Tablet Press

Tablet hardness testing ensures that tablets meet quality standards by balancing their mechanical strength with dissolution properties. This critical step prevents fragile tablets from breaking and overly hard tablets from compromising drug effectiveness.

 

What is Tablet Hardness Testing?

Tablet hardness testing measures the force needed to break a tablet. It ensures tablets are durable during production and transport while dissolving properly in the body to release active ingredients.

broken image

 

 

Why is Hardness Testing Important?

1. Prevents Breakage: Ensures tablets survive packaging and shipping.

2. Controls Drug Release: Influences how quickly the medication dissolves.

3. Ensures Compliance: Meets regulatory standards like USP <1217>.

Role of the Tablet Press Machine

The tablet press machine is key to controlling hardness. Adjusting compression force helps achieve the desired strength while maintaining other parameters like thickness.

 

Consequences of Neglecting Hardness Testing

1. Cracked or broken tablets during handling.

2. Delayed or inconsistent drug dissolution.

3. Regulatory non-compliance, leading to recalls.

 

Leading Manufacturers of Tablet Hardness Testers

Here are some reputable manufacturers offering a range of tablet hardness testers:

1. ERWEKA

Offers a variety of tablet hardness testers, from manual to fully automated systems, compliant with USP standards.

broken image

 

2. SOTAX

Provides precision Dr. Schleuniger® measuring technology for testing up to five physical parameters of tablets and capsules.

broken image

 

3. Teledyne

Offers both manual and automated tablet hardness testers designed to determine the mechanical properties of drug products.

 

broken image

 

4. Copley Scientific

Provides portable and simple-to-use tablet hardness testers ideal for quick checks of compression force in production areas.

 

broken image

 

5. Qualitest

Offers digital shore durometer hardness testers with manual and support-assisted operation for precise hardness testing.

 

broken image

 

Tablet hardness testing is a cornerstone of pharmaceutical quality control. Paired with optimized tablet press settings, it ensures high-quality, durable tablets that meet both consumer and regulatory expectations.

 

Previous
How Do Toothpaste Machines Make Your Favorite Toothpaste?
Next
How Can You Accurately Perform a Tablet Hardness Test?
 Return to site
Profile picture
Cancel
Cookie Use
We use cookies to improve browsing experience, security, and data collection. By accepting, you agree to the use of cookies for advertising and analytics. You can change your cookie settings at any time. Learn More
Accept all
Settings
Decline All
Cookie Settings
Necessary Cookies
These cookies enable core functionality such as security, network management, and accessibility. These cookies can’t be switched off.
Analytics Cookies
These cookies help us better understand how visitors interact with our website and help us discover errors.
Preferences Cookies
These cookies allow the website to remember choices you've made to provide enhanced functionality and personalization.
Save